Polymeric and elastomeric materials are commonly encountered in medical devices and
packaging systems used to manufacture, store, deliver, and/or administer drug products. …

We recently demonstrated that epinephrine could inhibit the activation by insulin of insulin
receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase (PI3-kinase) in skeletal …

The effect of carbohydrate supplementation on skeletal muscle glucose transporter GLUT-4
protein expression was studied in fast-twitch red and white gastrocnemius muscle of Sprague…

A simulating leaching (migration) study was performed on a model container-closure
system relevant to parenteral and ophthalmic drug products. This container-closure system …

Acute exercise and training increase insulin action in skeletal muscle, but the mechanism
responsible for this effect is unknown. Activation of the insulin receptor initiates signaling …

In the present study, we investigated the effects of chronic clenbuterol treatment on insulin-stimulated
glucose uptake in the presence of epinephrine in isolated rat skeletal muscle. …

Procedures and acceptance criteria for testing parenteral drug products are divided into two
categories:(1) those that assess product quality attributes (eg, identification, sterility, and …

β-Blockade results in rapid glucose clearance and premature fatigue during exercise. To
investigate the cause of this increased glucose clearance, we studied the acute effects of …

Since 1820, the US Pharmacopeial Convention established compendial standards for
drugs sold and marketed in the USA Currently these standards are published in the US …

In the present study we investigated the effects of chronic clenbuterol treatment on insulin-stimulated
glucose uptake in the presence of epinephrine in isolated rat skeletal muscle. …