[HTML][HTML] The anomalous magnetic moment of the muon in the Standard Model

T Aoyama, N Asmussen, M Benayoun, J Bijnens… - Physics reports, 2020 - Elsevier
We review the present status of the Standard Model calculation of the anomalous magnetic
moment of the muon. This is performed in a perturbative expansion in the fine-structure …

[HTML][HTML] Lipopolysaccharide structure and the phenomenon of low endotoxin recovery

A Gorman, AP Golovanov - European Journal of Pharmaceutics and …, 2022 - Elsevier
Lipopolysaccharide (LPS) is a cell-wall component of Gram-negative bacteria which
contributes to bacterial toxicity. During processes such as cell division, shedding of outer …

[HTML][HTML] Saving the horseshoe crab: A synthetic alternative to horseshoe crab blood for endotoxin detection

T Maloney, R Phelan, N Simmons - PLoS biology, 2018 - journals.plos.org
Horseshoe crabs have been integral to the safe production of vaccines and injectable
medications for the past 40 years. The bleeding of live horseshoe crabs, a process that …

[HTML][HTML] Comparison of LAL and rFC Assays—Participation in a Proficiency Test Program between 2014 and 2019

M Piehler, R Roeder, S Blessing, J Reich - Microorganisms, 2020 - mdpi.com
Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical
industries. Suitable compendial assays are defined by national pharmacopoeias. At this …

Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing

G Hannon, A Prina‐Mello - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Nanomaterials are highly susceptible to endotoxin contamination due their large surface‐to‐
volume ratios and endotoxins propensity to associate readily to hydrophobic and cationic …

[HTML][HTML] Atlantic horseshoe crabs and endotoxin testing: perspectives on alternatives, sustainable methods, and the 3Rs (replacement, reduction, and refinement)

R Gorman - Frontiers in Marine Science, 2020 - frontiersin.org
Endotoxin testing is a vital part of quality and safety control in pharmaceutical production.
The primary method for this testing in North America and Europe is the limulus amebocyte …

When would immunologists consider a nanomaterial to be safe? Recommendations for planning studies on nanosafety

M Himly, M Geppert, S Hofer, N Hofstätter… - Small, 2020 - Wiley Online Library
The immune system is professional in recognizing and responding to non‐self, including
nanomaterials. Immune responses by professional and nonprofessional immune cells are …

[HTML][HTML] Biomolecules of the Horseshoe Crab's Hemolymph: Components of an Ancient Defensive Mechanism and Its Impact on the Pharmaceutical and Biomedical …

M Ashrafuzzaman, MH Razu, NN Showva… - Cellular …, 2022 - hindawi.com
Without adaptive immunity, invertebrates have evolved innate immune systems that react to
antigens on the surfaces of pathogens. These defense mechanisms are included in …

Currently available recombinant alternatives to horseshoe crab blood lysates: Are they comparable for the detection of environmental bacterial endotoxins? A review

J Bolden, C Knutsen, J Levin, C Milne… - PDA Journal of …, 2020 - journal.pda.org
Endotoxin testing by recombinant factor C (rFC) is increasing with the addition of new
suppliers of reagents. By use of a recombinantly produced factor C, based on the sequence …

[HTML][HTML] Heparin enables the reliable detection of endotoxin in human serum samples using the Limulus amebocyte lysate assay

S Harm, C Schildböck, D Cont, V Weber - Scientific Reports, 2024 - nature.com
The determination of lipopolysaccharide (endotoxin) in serum or plasma samples using
Limulus amebocyte lysate (LAL)-based assays is currently not sufficiently reliable in clinical …