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Research ArticleResearch

Twenty plus Years of Data Demonstrating Virus Filtration as an Effective and Robust Step for Large Virus Removal

Brad Stanley, Veronica Holmes, Richard Manzari, Cara Romanowski, Anja Tessarz, Horst Ruppach and John Schreffler
PDA Journal of Pharmaceutical Science and Technology January 2022, 76 (1) 1-8; DOI: https://doi.org/10.5731/pdajpst.2020.012591
Brad Stanley
1Biogen, Inc., Process Biochemistry, 5000 Davis Drive, Research Triangle Park, NC;
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Veronica Holmes
2Janssen R&D LLC, Biotherapeutic Development API, 200 Great Valley Parkway, Malvern, PA;
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Richard Manzari
3WuXi Advanced Therapies, Viral Clearance, 4751 League Island Boulevard, Philadelphia, PA; and
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Cara Romanowski
3WuXi Advanced Therapies, Viral Clearance, 4751 League Island Boulevard, Philadelphia, PA; and
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Anja Tessarz
4Charles River Laboratories Germany GmbH, Biologics Testing, Gottfried-Hagen Strasse 20, 51105 Köln, Germany
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Horst Ruppach
4Charles River Laboratories Germany GmbH, Biologics Testing, Gottfried-Hagen Strasse 20, 51105 Köln, Germany
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John Schreffler
2Janssen R&D LLC, Biotherapeutic Development API, 200 Great Valley Parkway, Malvern, PA;
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  • For correspondence: jschreff@its.jnj.com
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PDA Journal of Pharmaceutical Science and Technology: 76 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 76, Issue 1
January/February 2022
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Twenty plus Years of Data Demonstrating Virus Filtration as an Effective and Robust Step for Large Virus Removal
Brad Stanley, Veronica Holmes, Richard Manzari, Cara Romanowski, Anja Tessarz, Horst Ruppach, John Schreffler
PDA Journal of Pharmaceutical Science and Technology Jan 2022, 76 (1) 1-8; DOI: 10.5731/pdajpst.2020.012591

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Twenty plus Years of Data Demonstrating Virus Filtration as an Effective and Robust Step for Large Virus Removal
Brad Stanley, Veronica Holmes, Richard Manzari, Cara Romanowski, Anja Tessarz, Horst Ruppach, John Schreffler
PDA Journal of Pharmaceutical Science and Technology Jan 2022, 76 (1) 1-8; DOI: 10.5731/pdajpst.2020.012591
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Keywords

  • Virus filtration
  • Modular viral clearance
  • Small virus retentive filter
  • Large virus retentive filter
  • Viral clearance
  • Murine leukemia virus (MuLV)
  • Reovirus (Reo-3)
  • Pseudorabies virus (PrV)

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