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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System

Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen and Natarajan Rajagopalan
PDA Journal of Pharmaceutical Science and Technology October 2017, pdajpst.2017.008169; DOI: https://doi.org/10.5731/pdajpst.2017.008169
Galen H. Shi
Eli Lilly and Company
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  • For correspondence: shi_galen_huaiqiu{at}lilly.com
Sharon L. Shinkle
Eli Lilly and Company
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Ganapathy Gopalrathnam
Eli Lilly and Company
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Xia Dong
Eli Lilly and Company
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Jeffrey D. Hofer
Eli Lilly and Company
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Eric C. Jensen
Eli Lilly and Company
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Natarajan Rajagopalan
Eli Lilly and Company
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  • For correspondence: rajagopalan_natarajan{at}lilly.com
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Article Information

pdajpst.2017.008169
DOI 
https://doi.org/10.5731/pdajpst.2017.008169
PubMed 
29030531

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Received July 18, 2017
  • Accepted October 10, 2017
  • Published online October 12, 2017.

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  • You are currently viewing a previous version of this article (October 12, 2017 - 19:14).
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Copyright & Usage 
Copyright © 2017, Parenteral Drug Association

Author Information

  1. Galen H. Shi (shi_galen_huaiqiu{at}lilly.com) (www.lilly.com),
  2. Sharon L. Shinkle (shinkle_sharon_l{at}lilly.com) (www.lilly.com),
  3. Ganapathy Gopalrathnam (gopalrathnam_ganapathy{at}lilly.com) (www.lilly.com),
  4. Xia Dong (dong_xia{at}lilly.com) (www.lilly.com),
  5. Jeffrey D. Hofer (hofer_jeffrey_d{at}lilly.com) (www.lilly.com),
  6. Eric C. Jensen (jensen_eric_c{at}lilly.com) (www.lilly.com) and
  7. Natarajan Rajagopalan1 (rajagopalan_natarajan{at}lilly.com) (www.lilly.com)
  1. Eli Lilly and Company
  1. ↵* Corresponding author; email: rajagopalan_natarajan{at}lilly.com

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PDA Journal of Pharmaceutical Science and Technology: 79 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 79, Issue 5
September/October 2025
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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System
Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen, Natarajan Rajagopalan
PDA Journal of Pharmaceutical Science and Technology Oct 2017, pdajpst.2017.008169; DOI: 10.5731/pdajpst.2017.008169

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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System
Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen, Natarajan Rajagopalan
PDA Journal of Pharmaceutical Science and Technology Oct 2017, pdajpst.2017.008169; DOI: 10.5731/pdajpst.2017.008169
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Keywords

  • Formulation development
  • functionality
  • Glide force
  • monoclonal antibodies
  • Prefilled syringe
  • silicone

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