%0 Journal Article %A Aditya Prasad %A Philip Villari %A Robert 'Bo' Henry %A Jeffrey Weber %A James Hauschild %A Lisa Yan %A Jeff Horsch %A Shebeer Shereefa %A Jan Eric Rau %A Annett Milling %A Jay S Bolden %A Lucile Plourde %A Marja Claassen %A Pieta IJzerman-Boon %A Ren-Yo Forng %A Roland Portmann %A Simon Urwyler %A Dawood Dassu %T Practical applications of bio-fluorescent particle counting in Environmental Monitoring investigations %D 2019 %R 10.5731/pdajpst.2019.009969 %J PDA Journal of Pharmaceutical Science and Technology %P pdajpst.2019.009969 %X Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or CAPAs. This paper outlines how bio-fluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM; acting as a risk reduction tool enabling real-time detection of viable microorganisms in air samples − supporting root cause analysis and remedial actions. The paper includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies. %U https://journal.pda.org/content/pdajpst/early/2019/12/13/pdajpst.2019.009969.full.pdf