PT  - JOURNAL ARTICLE
AU  - Aditya Prasad
AU  - Philip Villari
AU  - Robert 'Bo' Henry
AU  - Jeffrey Weber
AU  - James Hauschild
AU  - Lisa Yan
AU  - Jeff Horsch
AU  - Shebeer Shereefa
AU  - Jan Eric Rau
AU  - Annett Milling
AU  - Jay S Bolden
AU  - Lucile Plourde
AU  - Marja Claassen
AU  - Pieta IJzerman-Boon
AU  - Ren-Yo Forng
AU  - Roland Portmann
AU  - Simon Urwyler
AU  - Dawood Dassu
TI  - Practical applications of bio-fluorescent particle counting in Environmental Monitoring investigations
AID  - 10.5731/pdajpst.2019.009969
DP  - 2019 Jan 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - pdajpst.2019.009969
4099  - http://journal.pda.org/content/early/2019/12/13/pdajpst.2019.009969.short
4100  - http://journal.pda.org/content/early/2019/12/13/pdajpst.2019.009969.full
AB  - Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or CAPAs. This paper outlines how bio-fluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM; acting as a risk reduction tool enabling real-time detection of viable microorganisms in air samples − supporting root cause analysis and remedial actions. The paper includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.