PT  - JOURNAL ARTICLE
AU  - Prasad, Aditya
AU  - Villari, Philip
AU  - Henry, Robert 'Bo'
AU  - Weber, Jeffrey
AU  - Hauschild, James
AU  - Yan, Lisa
AU  - Horsch, Jeff
AU  - Shereefa, Shebeer
AU  - Rau, Jan Eric
AU  - Milling, Annett
AU  - Bolden, Jay S
AU  - Plourde, Lucile
AU  - Claassen, Marja
AU  - IJzerman-Boon, Pieta
AU  - Forng, Ren-Yo
AU  - Portmann, Roland
AU  - Urwyler, Simon
AU  - Dassu, Dawood
TI  - Practical applications of bio-fluorescent particle counting in Environmental Monitoring investigations
AID  - 10.5731/pdajpst.2019.009969
DP  - 2019 Jan 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - pdajpst.2019.009969
4099  - http://journal.pda.org/content/early/2019/12/13/pdajpst.2019.009969.short
4100  - http://journal.pda.org/content/early/2019/12/13/pdajpst.2019.009969.full
AB  - Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or CAPAs. This paper outlines how bio-fluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM; acting as a risk reduction tool enabling real-time detection of viable microorganisms in air samples − supporting root cause analysis and remedial actions. The paper includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.