RT Journal Article
SR Electronic
T1 Practical Applications of Biofluorescent Particle Counting in Environmental Monitoring Investigations
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 318
OP 323
DO 10.5731/pdajpst.2019.009969
VO 74
IS 3
A1 Prasad, Aditya
A1 Villari, Philip
A1 Henry, Robert “Bo”
A1 Weber, Jeffrey
A1 Hauschild, James
A1 Yan, Lisa
A1 Horsch, Jeff
A1 Shereefa, Shebeer
A1 Rau, Jan Erik
A1 Milling, Annett
A1 Bolden, Jay S.
A1 Plourde, Lucile
A1 Claassen, Marja
A1 IJzerman-Boon, Pieta
A1 Forng, Ren-Yo
A1 Portmann, Roland
A1 Urwyler, Simon
A1 Dassu, Dawood
YR 2020
UL http://journal.pda.org/content/74/3/318.abstract
AB Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or corrective and preventative actions. This article outlines how biofluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM, acting as a risk-reduction tool enabling real-time detection of viable microorganisms in air samples and supporting root cause analysis and remedial actions. The article includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.