RT Journal Article SR Electronic T1 Practical Applications of Biofluorescent Particle Counting in Environmental Monitoring Investigations JF PDA Journal of Pharmaceutical Science and Technology JO PDA J Pharm Sci Technol FD Parenteral Drug Association (PDA) SP 318 OP 323 DO 10.5731/pdajpst.2019.009969 VO 74 IS 3 A1 Aditya Prasad A1 Philip Villari A1 Robert “Bo” Henry A1 Jeffrey Weber A1 James Hauschild A1 Lisa Yan A1 Jeff Horsch A1 Shebeer Shereefa A1 Jan Erik Rau A1 Annett Milling A1 Jay S. Bolden A1 Lucile Plourde A1 Marja Claassen A1 Pieta IJzerman-Boon A1 Ren-Yo Forng A1 Roland Portmann A1 Simon Urwyler A1 Dawood Dassu YR 2020 UL http://journal.pda.org/content/74/3/318.abstract AB Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or corrective and preventative actions. This article outlines how biofluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM, acting as a risk-reduction tool enabling real-time detection of viable microorganisms in air samples and supporting root cause analysis and remedial actions. The article includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.