RT Journal Article SR Electronic T1 Continuous and Effective Microbiological Air Monitoring in Critical Environments: A Comparison of Analytical Methodologies JF PDA Journal of Pharmaceutical Science and Technology JO PDA J Pharm Sci Technol FD Parenteral Drug Association (PDA) SP 446 OP 455 DO 10.5731/pdajpst.2019.010181 VO 74 IS 4 A1 Dalmaso, Gilberto A1 Campanella, Anna A1 Lazzeri, Paola YR 2020 UL http://journal.pda.org/content/74/4/446.abstract AB Manufacture of sterile products must strictly follow carefully established and validated analytical methods of manufacture and control. Based on this consideration, we evaluated scientific literature describing settle plates and active air sampler monitoring effectiveness. A contamination control strategy should be implemented by pharma manufacturers, especially for aseptic productions, to assess the effectiveness of environmental monitoring and demonstrate that the process is under statistical control. It is of key importance for microbiological monitoring data to correlate as best as possible with total particle monitoring data so that each batch release is reliably supported.