PT  - JOURNAL ARTICLE
AU  - Ljungqvist, Bengt
AU  - Reinmüller, Berit
TI  - People as a Contamination Source in Pharmaceutical Cleanrooms –Source Strengths and Calculated Concentrations of Airborne Contaminants
AID  - 10.5731/pdajpst.2020.012054
DP  - 2020 Jan 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - pdajpst.2020.012054
4099  - http://journal.pda.org/content/early/2020/09/30/pdajpst.2020.012054.short
4100  - http://journal.pda.org/content/early/2020/09/30/pdajpst.2020.012054.full
AB  - People as a Contamination Source in Pharmaceutical Cleanrooms −Source Strengths and Calculated Concentrations of Airborne Contaminants BENGT LJUNGQVIST AND BERIT REINMÜLLER Building Services Engineering, Chalmers University of Technology, Göteborg, Sweden Corresponding author: Berit Reinmüller, Building Services Engineering, Architecture and Civil Engineering, Chalmers University of Technology, SE SE-41296 Göteborg, Sweden e-mail: beritr@chalmers.se ABSTRACT Results are presented from studies performed in a test chamber on cleanroom garments used, laundered, and sterilized (autoclaved 20 minutes at 121°C), 50, 60, and 70 times, and garments used, laundered, and sterilized with a prolonged autoclave cycle 50 times. The source strength is described as the mean value of the number per second of airborne particles and aerobic CFU, respectively, emitted from one person dressed in the system to be evaluated. Results from body-box tests have been used to calculate theoretical expected concentrations of airborne aerobic CFU and particles (≥0.5µm) in cleanrooms with different number of people present, and at different airflows (m3/s.). Theoretical expected concentrations of airborne aerobic CFU are often below the detection level of traditional measuring equipment. .