PT  - JOURNAL ARTICLE
AU  - Ira C. Peine
AU  - John C. Swenson
AU  - Jorn Dan Benedictus
TI  - Automation of an Ultrafiltration System in the Plasma Fractionation Industry
DP  - 1982 Mar 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 79--85
VI  - 36
IP  - 2
4099  - http://journal.pda.org/content/36/2/79.short
4100  - http://journal.pda.org/content/36/2/79.full
SO  - PDA J Pharm Sci Technol1982 Mar 01; 36
AB  - Ultrafiltration, as an alternate technology to thin film evaporation and lyophilization for the processing of plasma proteins, has created a need for a unique control and monitoring system. Existing "off the shelf microcomputer technology made the design of such control much simpler than developing similar control utilizing discrete electric mechanical components. Process control, monitoring, and recording is accomplished by using sanitary sensors for pressure, temperature, level, conductivity, flow, and UF absorption, whose outputs are processed by a programmable controller. Flow control is accomplished by a controller-averaged pressure signal and a feedback loop. Automatic control, monitoring, and recording address the need to design in quality, reliability, traceability, and accountability.