RT Journal Article
SR Electronic
T1 Automation of an Ultrafiltration System in the Plasma Fractionation Industry
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 79
OP 85
VO 36
IS 2
A1 Ira C. Peine
A1 John C. Swenson
A1 Jorn Dan Benedictus
YR 1982
UL http://journal.pda.org/content/36/2/79.abstract
AB Ultrafiltration, as an alternate technology to thin film evaporation and lyophilization for the processing of plasma proteins, has created a need for a unique control and monitoring system. Existing "off the shelf microcomputer technology made the design of such control much simpler than developing similar control utilizing discrete electric mechanical components. Process control, monitoring, and recording is accomplished by using sanitary sensors for pressure, temperature, level, conductivity, flow, and UF absorption, whose outputs are processed by a programmable controller. Flow control is accomplished by a controller-averaged pressure signal and a feedback loop. Automatic control, monitoring, and recording address the need to design in quality, reliability, traceability, and accountability.