PT  - JOURNAL ARTICLE
AU  - Myers, Ted
AU  - Chrai, Suggy
TI  - Steam-In-Place Sterilization of Cartridge Filters In-Line with a Receiving Tank
DP  - 1982 May 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 108--112
VI  - 36
IP  - 3
4099  - http://journal.pda.org/content/36/3/108.short
4100  - http://journal.pda.org/content/36/3/108.full
SO  - PDA J Pharm Sci Technol1982 May 01; 36
AB  - An approach is described for the design and evaluation of a steam-in-place (SIP) process for the in-line sterilization of cartridge filters with a receiving tank. The process and system evaluated was designed to provide for complete non-aseptic assembly, reproducibly deliver a known assurance of sterility without compromising filter integrity, and provide a versatility for a variety of filter elements. Also examined were the influence of filter housing design and orientation on the sterilization process, steaming filters wet vs dry, and different types of filter media.