RT Journal Article
SR Electronic
T1 Steam-In-Place Sterilization of Cartridge Filters In-Line with a Receiving Tank
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 108
OP 112
VO 36
IS 3
A1 Myers, Ted
A1 Chrai, Suggy
YR 1982
UL http://journal.pda.org/content/36/3/108.abstract
AB An approach is described for the design and evaluation of a steam-in-place (SIP) process for the in-line sterilization of cartridge filters with a receiving tank. The process and system evaluated was designed to provide for complete non-aseptic assembly, reproducibly deliver a known assurance of sterility without compromising filter integrity, and provide a versatility for a variety of filter elements. Also examined were the influence of filter housing design and orientation on the sterilization process, steaming filters wet vs dry, and different types of filter media.