RT Journal Article
SR Electronic
T1 An Application of the Negative Binomial Distribution to a Problem in Microbiologically Clean Area Testing
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 237
OP 241
VO 36
IS 6
A1 Lee, Martin L.
A1 Kantrowitz, Julia L.
A1 Ellis, Joyce E.
YR 1982
UL http://journal.pda.org/content/36/6/237.abstract
AB A method is discussed for monitoring areas that must be biologically clean. A negative binomial distribution was used to analyze data derived from the number of colonies formed on blood agar plates exposed in such areas for varying lengths of time. From this analysis, an upper bound for the number of colonies formed per hour was generated, which conformed to the NASA specifications for any given class of microbiologically clean areas.