PT  - JOURNAL ARTICLE
AU  - Lindstrom, Richard E.
AU  - Patel, Sureshchandra N.
AU  - Wilkinson, Paul K.
TI  - The Determination of Oxygen in Aqueous Solution: A Review of Methods
DP  - 1980 Jan 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 5--13
VI  - 34
IP  - 1
4099  - http://journal.pda.org/content/34/1/5.short
4100  - http://journal.pda.org/content/34/1/5.full
SO  - PDA J Pharm Sci Technol1980 Jan 01; 34
AB  - The review centers on chemical, chromatographic, and electrometric methods of oxygen analysis used in the study of parenteral solutions. Basic principles in each of the methods of analysis are presented along with indications of their sensitivities, advantages, and drawbacks. The past and current literature shows the Winkler method to be the bench mark for the development or modification of virtually any technique for dissolved oxygen measurements. Electrometric methods, most notably that using the membrane covered polarographic detector, appear to be the most promising in terms of generating rapid, accurate results.