TY - JOUR T1 - A Novel Sampling System for 12/88 Sterilizing Gas Mixture JF - PDA Journal of Pharmaceutical Science and Technology JO - PDA J Pharm Sci Technol SP - 70 LP - 79 VL - 34 IS - 1 AU - Arthur E. Holmer AU - Ronald W. Shrewsbury Y1 - 1980/01/01 UR - http://journal.pda.org/content/34/1/70.abstract N2 - Various sampling devices for the liquefied sterilizing gas mixture of 12 wt % ethylene oxide, 88 wt % dichlorodifluoromethane (“12-88’) were designed and tested. Devices were evaluated on integrity of mixture concentration, ease of operation, and adaptability to common analytical equipment. The optimum design was further evaluated over a range of ethylene oxide concentrations to ascertain performance in regions other than 12 wt %. A gas chromatography analytical technique was employed. ER -