PT - JOURNAL ARTICLE AU - Glenn Howard, Jr AU - Ronnie Duberstein TI - A Case of Penetration of 0.2-µm Rated Membrane Filters by Bacteria DP - 1980 Mar 01 TA - PDA Journal of Pharmaceutical Science and Technology PG - 95--102 VI - 34 IP - 2 4099 - http://journal.pda.org/content/34/2/95.short 4100 - http://journal.pda.org/content/34/2/95.full SO - PDA J Pharm Sci Technol1980 Mar 01; 34 AB - While conducting long term bacteria challenge tests of 0.2-µ.m rated sterilizing grade filters which retained 100% of the standard challenge organism P. diminuta, it was discovered that several species of indigenous water bacteria were not completely retained by these filters. This finding has been confirmed for a variety of commercially available Q.2-µm rated disc and cartridge filters. Filters were challenged with wellwater which contained naturally occurring bacterial species. The challenge system included a prefilter to remove debris and large microorganisms, the test filter, and an analysis membrane filter to monitor the total effluent. Influent bacteria levels were also