RT Journal Article
SR Electronic
T1 Recovery of Biological Indicator Organisms after Sublethal Sterilization Treatment
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 394
OP 397
VO 34
IS 5
A1 Caputo, ROSS A.
A1 Rohn, Kimberly J.
A1 Mascoli, Carmine C.
YR 1980
UL http://journal.pda.org/content/34/5/394.abstract
AB An important factor affecting the recovery of biological indicators (BI’s) is the time elapsed between exposure to a sterilant and growth testing. The length of time and the temperature at which the BI’s are stored after sterilization were found to significantly affect growth. BI’s stored at 20–25 °C for 48 hr prior to testing showed a 90% reduction in growth when compared to those that had been refrigerated at 2–8 °Cfor the same time period. This was consistent for B. subtilis and B. stcarothermophilus spores and independent of the type of sterilization process studied.