RT Journal Article
SR Electronic
T1 Rubber Stopper and Component Identification Using Syringeless Gas Chromatography
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 436
OP 446
VO 34
IS 6
A1 Mattson, Leland N.
A1 Gaebler, Robert N.
A1 Giebe, Kenneth E.
A1 Peppers, Ralph E.
YR 1980
UL http://journal.pda.org/content/34/6/436.abstract
AB The quality control of rubber stoppers and syringe components has been generally limited to tests covered in P.D.A. Information Bulletin No. 2, which lists procedures for ash, specific gravity, infrared spectrophotometry of pyrozalate, and ultraviolet spectrophotometry of extracts. This paper presents a possible new technique for evaluating these components for identity, stability, absorbed preservatives and formulation ingredients using syringeless gas chromatography.