@article {Hickey244, author = {Thomas E. Hickey}, title = {The Johns Hopkins Center for Alternatives to Animal Testing{\textemdash}An Update}, volume = {37}, number = {6}, pages = {244--246}, year = {1983}, publisher = {Parenteral Drug Association (PDA)}, abstract = {The primary mission of the Johns Hopkins Center for Alternatives to Animal Testing is to develop a fundamental knowledge-base that will provide alternative methods to whole animal testing. A goal of the Center is to develop appropriate basic scientific knowledge for innovative methods to evaluate fully the safety of commercial and/or therapeutic products. An active research program is underway which will provide data on mechanisms of toxicity. Current research encompasses three areas: responses of specific cell systems, membrane structure and function, and secretory responses of cells and organs. Grant proposals are subjected to a scientific review process and must be approved by the Center Advisory Board. An annual symposium serves to shape the research approach and identify the research program. A periodic newsletter enhances communication to the scientific community and general public.}, issn = {0006-3363}, URL = {https://journal.pda.org/content/37/6/244}, eprint = {https://journal.pda.org/content/37/6/244.full.pdf}, journal = {PDA Journal of Pharmaceutical Science and Technology} }