PT  - JOURNAL ARTICLE
AU  - Thomas E. Hickey
TI  - The Johns Hopkins Center for Alternatives to Animal Testing—An Update
DP  - 1983 Nov 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 244--246
VI  - 37
IP  - 6
4099  - http://journal.pda.org/content/37/6/244.short
4100  - http://journal.pda.org/content/37/6/244.full
SO  - PDA J Pharm Sci Technol1983 Nov 01; 37
AB  - The primary mission of the Johns Hopkins Center for Alternatives to Animal Testing is to develop a fundamental knowledge-base that will provide alternative methods to whole animal testing. A goal of the Center is to develop appropriate basic scientific knowledge for innovative methods to evaluate fully the safety of commercial and/or therapeutic products. An active research program is underway which will provide data on mechanisms of toxicity. Current research encompasses three areas: responses of specific cell systems, membrane structure and function, and secretory responses of cells and organs. Grant proposals are subjected to a scientific review process and must be approved by the Center Advisory Board. An annual symposium serves to shape the research approach and identify the research program. A periodic newsletter enhances communication to the scientific community and general public.