PT - JOURNAL ARTICLE AU - Kanneg1Eter, E. M. AU - Baggerman, C. TI - A New Method to Reduce Electrolyte Inhibition of the Detection of Endotoxins in Large Volume Parenterals DP - 1984 Jan 01 TA - PDA Journal of Pharmaceutical Science and Technology PG - 17--20 VI - 38 IP - 1 4099 - http://journal.pda.org/content/38/1/17.short 4100 - http://journal.pda.org/content/38/1/17.full SO - PDA J Pharm Sci Technol1984 Jan 01; 38 AB - A new method is described for the quantitative detection of endotoxins in large volume parenterals, based on the use of limulus amoebocyte lysate in combination with a chromogenic substrate. Inhibitory effects caused by the presence of electrolytes, can be eliminated by the use of an endotoxin-dispersion-stabilizing-agent, except in case highly concentrated salt solutions are involved.