PT  - JOURNAL ARTICLE
AU  - Weary, Marlys
TI  - Pyrogen Testing of Parenteral Products—Status Report
DP  - 1984 Jan 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 20--23
VI  - 38
IP  - 1
4099  - http://journal.pda.org/content/38/1/20.short
4100  - http://journal.pda.org/content/38/1/20.full
SO  - PDA J Pharm Sci Technol1984 Jan 01; 38
AB  - The current status of the Limulus Amebocyte Lysate (LAL) test for final release of drug products and devices in the United States and abroad is discussed. The principal problem dealt with is determining an endotoxin limit for the LAL assay. This is significant because the LAL test is more sensitive than the USP rabbit pyrogen test, and because, as comparative LAL and rabbit assays indicate, purified endotoxin standard is more pyrogenic than environmental endotoxin.