RT Journal Article
SR Electronic
T1 Degradation of Tryptophan in Aqueous Solution
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 20
OP 22
VO 42
IS 1
A1 M. G. Lee
A1 C. M. Rogers
YR 1988
UL http://journal.pda.org/content/42/1/20.abstract
AB The degradation rate of tryptophan is increased by light and in the presence of oxygen and sodium metabisulfite. Light catalyzes the action of oxygen and sodium metabisulfite but will also initiate an autooxidation process in the absence of these two. Tryptophan does not react with sodium metabisulfite alone, oxygen must also be present. The rate of this reaction is greater than that between tryptophan and light or oxygen alone.