PT  - JOURNAL ARTICLE
AU  - Barrett E. Rabinow
AU  - Scott Ericson
AU  - Tim Shelborne
TI  - Aluminum in Parenteral Products: Analysis, Reduction, and Implications for Pediatric TPN
DP  - 1989 May 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 132--139
VI  - 43
IP  - 3
4099  - http://journal.pda.org/content/43/3/132.short
4100  - http://journal.pda.org/content/43/3/132.full
SO  - PDA J Pharm Sci Technol1989 May 01; 43
AB  - Performance and cost of the best available analytical methodology for the measurement of aluminum in parenteral products are presented. Typical levels of aluminum in representative solutions are summarized. A methodical approach to the minimization of aluminum contamination in the manufacturing process is considered in light of aqueous aluminum chemical considerations. Results of long-term clinical follow-up studies of infants maintained on currently manufactured TPN solutions indicate no adverse pathology arising from aluminum.