TY - JOUR T1 - Aluminum in Parenteral Products: Analysis, Reduction, and Implications for Pediatric TPN JF - PDA Journal of Pharmaceutical Science and Technology JO - PDA J Pharm Sci Technol SP - 132 LP - 139 VL - 43 IS - 3 AU - Barrett E. Rabinow AU - Scott Ericson AU - Tim Shelborne Y1 - 1989/05/01 UR - http://journal.pda.org/content/43/3/132.abstract N2 - Performance and cost of the best available analytical methodology for the measurement of aluminum in parenteral products are presented. Typical levels of aluminum in representative solutions are summarized. A methodical approach to the minimization of aluminum contamination in the manufacturing process is considered in light of aqueous aluminum chemical considerations. Results of long-term clinical follow-up studies of infants maintained on currently manufactured TPN solutions indicate no adverse pathology arising from aluminum. ER -