RT Journal Article
SR Electronic
T1 Microwave Sterilization of Vials
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 25
OP 30
VO 40
IS 1
A1 Lohmann, Soren
A1 Manique, Flemming
YR 1986
UL http://journal.pda.org/content/40/1/25.abstract
AB Due to different dielectric loss factors between glass and cell tissue, microwaves should primarily heat the microorganisms without intensive heating of the vials. A time and energy saving method for sterilization should therefore be possible by the use of microwave heating. Spores of B. subtilis and B. Stearothermophilus were applied to the vials which were treated with microwaves for different periods of time. The reduction of microorganisms by microwave treatment was determined. The reduction factor for B. subtilis was determined to more than 1O12 within 3 min of treatment with microwaves.