RT Journal Article
SR Electronic
T1 The Difficulties of Drawing Blood from Venous Catheters; A Hydraulic Model
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 3
OP 8
VO 41
IS 1
A1 Roberts, R. K.
A1 Hillberry, B. M.
A1 Thornhill, J. A.
A1 Blevins, W. E.
A1 Ash, S. R.
YR 1987
UL http://journal.pda.org/content/41/1/3.abstract
AB It is common knowledge that it is much easier to infuse fluid to a venous catheter than to withdraw blood from it. Venous catheters from which blood must be drawn quickly are usually of large size and have numerous side holes. The exact design is usually evolved through “trial and error,“ and the venous removal catheters still occasionally occlude during outflow. The purpose of this paper is to explain the genesis of outflow obstruction, and to quantitate the resistance and tendency of several catheters to occlude. Flow and pressure data are presented from experiments with jugular-vena cava catheters in dogs, and from an in vitro model with an artificial material simulating a vein. From this data, a mathematical model of the vein and catheter is developed. This type of study can be useful in design and testing of radically different approaches to vascular access.