PT  - JOURNAL ARTICLE
AU  - Aicholtz, Pat
AU  - Wilkins, Randy
AU  - Gabler, Raymond
TI  - Sterile Filtration Under Conditions of High Pressure and Bacterial Challenge Levels
DP  - 1987 Jul 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 117--120
VI  - 41
IP  - 4
4099  - http://journal.pda.org/content/41/4/117.short
4100  - http://journal.pda.org/content/41/4/117.full
SO  - PDA J Pharm Sci Technol1987 Jul 01; 41
AB  - Experiments were performed to determine if sterilizing grade cartridge filters can retain bacteria under conditions of high challenge conditions and high pressure. In all cases the sterilizing grade filters, which passed the integrity test retained all bacteria even though the differential pressures exceeded the manufacturer’s recommended maximum continuous operating pressure. Under similar operating conditions 0.45 micron rated cartridges did not retain all bacteria.