RT Journal Article
SR Electronic
T1 Boundary and Airlock Design Issues in Aseptic Facilities
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 279
OP 285
VO 45
IS 6
A1 Lorenz, Michael R.
A1 Robinson, John E.
YR 1991
UL http://journal.pda.org/content/45/6/279.abstract
AB As more potentially hazardous biopharmaceutical and powder derivative products are being processed aseptically, the term “ontainment” in aseptic facility design must take on a broader definition. Contamination control must address not only protection of the product, but the protection of aseptic facility workers and of the surrounding environment as well. This paper will focus on design issues related to the physical boundaries (walls, ceilings, doors, etc.) that separate aseptic areas from other spaces within a facility with particular emphasis on the design of airlocks as “control points” for contamination control.