PT  - JOURNAL ARTICLE
AU  - Martin A. Joyce
AU  - Jeffrey W. Lorenz
TI  - Computer Interface for Vial Sealing Force Measurements
DP  - 1990 Mar 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 54--57
VI  - 44
IP  - 2
4099  - http://journal.pda.org/content/44/2/54.short
4100  - http://journal.pda.org/content/44/2/54.full
SO  - PDA J Pharm Sci Technol1990 Mar 01; 44
AB  - The force applied to the closure of a parenteral container is a critical parameter in assuring the integrity of a seal. Measurement of the force can be accomplished either off line, through residual force measurements, or on line, through instrumentation of the sealing station. The instrumentation of the sealing station provides a dynamic profile of the sealing event for development of the optimal sealing parameters. A computer interface for this application has been developed using a standard IBM-AT and commercially available data acquisition hardware and software. The resultant data can be set up in Lotus I -2-3, or any other analysis package capable of importing ASCII files, for graphic display, and/or additional analysis. The system thus provides a means to acquire quantitative data on the sealing event for development of optimal sealing parameters.