RT Journal Article
SR Electronic
T1 Computer Interface for Vial Sealing Force Measurements
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 54
OP 57
VO 44
IS 2
A1 Joyce, Martin A.
A1 Lorenz, Jeffrey W.
YR 1990
UL http://journal.pda.org/content/44/2/54.abstract
AB The force applied to the closure of a parenteral container is a critical parameter in assuring the integrity of a seal. Measurement of the force can be accomplished either off line, through residual force measurements, or on line, through instrumentation of the sealing station. The instrumentation of the sealing station provides a dynamic profile of the sealing event for development of the optimal sealing parameters. A computer interface for this application has been developed using a standard IBM-AT and commercially available data acquisition hardware and software. The resultant data can be set up in Lotus I -2-3, or any other analysis package capable of importing ASCII files, for graphic display, and/or additional analysis. The system thus provides a means to acquire quantitative data on the sealing event for development of optimal sealing parameters.