RT Journal Article
SR Electronic
T1 Operational Aspects of Bioreactor Contamination Control
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 113
OP 117
VO 44
IS 3
A1 Perkowski, Casimir A.
YR 1990
UL http://journal.pda.org/content/44/3/113.abstract
AB The contamination-free operation of a bioreactor demands constant attention to details. Assuming a well-designed and validated system exists, contamination control requires a skilled operating staff clear and concise standard operating procedures, ongoing operations review and training, thorough cleaning of equipment, and an effective preventative maintenance program. This paper highlights basic operational aspects of contaminant-free bioreactor operation from inoculum development to bioreactor harvesting.