RT Journal Article
SR Electronic
T1 Quantitative Evaluation of the Stability and Delivery of lnterleukin-1 B by Infusion
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 130
OP 132
VO 44
IS 3
A1 Visor, Gary C.
A1 Tsai, Kelly P.
A1 Duffy, Jane
A1 Miller, Mary D.
A1 Calderwood, Tom
A1 Knepp, Victoria M.
YR 1990
UL http://journal.pda.org/content/44/3/130.abstract
AB The stability and delivery of IL-1β has been characterized in a polypropylene based syringe pump infusion system and in polyvinyl chloride based infusion bags, at concentrations ranging from 100 μg/ mL to I μg/mL. At higher concentrations (1μg/mL). minimal drug loss was observed in both systems. At low doses (100 μg/mL) in the syringe-pump system, the addition of 1% human serum albumin was necessary to prevent significant drug adsorption to the polypropylene drug reservoir.