PT - JOURNAL ARTICLE AU - Agalloco, James TI - Steam Sterilization-in-Place Technology DP - 1990 Sep 01 TA - PDA Journal of Pharmaceutical Science and Technology PG - 253--256 VI - 44 IP - 5 4099 - http://journal.pda.org/content/44/5/253.1.short 4100 - http://journal.pda.org/content/44/5/253.1.full SO - PDA J Pharm Sci Technol1990 Sep 01; 44 AB - Steam sterilization-in-place (more commonly known by its acronym as SIP) is coming into wider usage within the pharmaceutical and biotechnology industries as firms endeavor to increase the level of sterility assurance associated with those products made by aseptic processing. Despite this increase in interest, sterilization-in-place has not been given the attention its growing importance appears to warrant. The intent of this presentation is to define the overall concepts involved with the application of SIP technology and review how these concerns affect specific systems.