PT  - JOURNAL ARTICLE
AU  - Joyce, Martin A.
AU  - Lorenz, Jeffrey W.
TI  - Internal Pressure of Sealed Containers During Autoclaving
DP  - 1990 Nov 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 320--323
VI  - 44
IP  - 6
4099  - http://journal.pda.org/content/44/6/320.short
4100  - http://journal.pda.org/content/44/6/320.full
SO  - PDA J Pharm Sci Technol1990 Nov 01; 44
AB  - The use of steam as a sterilizing media for rigid, fixed volume containers is routine. When applied to less rigorous packages this process can cause package failure and product contamination or loss. A study has been carried out verifying the validity of a previously developed equation by measuring the actual pressures generated during sterilization in a small container system.