RT Journal Article
SR Electronic
T1 Internal Pressure of Sealed Containers During Autoclaving
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 320
OP 323
VO 44
IS 6
A1 Joyce, Martin A.
A1 Lorenz, Jeffrey W.
YR 1990
UL http://journal.pda.org/content/44/6/320.abstract
AB The use of steam as a sterilizing media for rigid, fixed volume containers is routine. When applied to less rigorous packages this process can cause package failure and product contamination or loss. A study has been carried out verifying the validity of a previously developed equation by measuring the actual pressures generated during sterilization in a small container system.