PT  - JOURNAL ARTICLE
AU  - Priscilla F. Roslansky
AU  - Michael E. Dawson
AU  - Thomas J. Novitsky
TI  - Plastics, Endotoxins, and the Limulus Amebocyte Lysate Test
DP  - 1991 Mar 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 83--87
VI  - 45
IP  - 2
4099  - http://journal.pda.org/content/45/2/83.short
4100  - http://journal.pda.org/content/45/2/83.full
SO  - PDA J Pharm Sci Technol1991 Mar 01; 45
AB  - A variety of polypropylene and polystyrene tubes have been tested for use with the Limulus amebocyte lysate (LAV) test. Polypropylene tubes tended vo be more contaminated with endotoxin than polystyrene. One brand of polypropylene tube contained a water extractable inhibitor of the LAL test. Polystyrene tubes from some manufacturers caused enhancement of the LAL test. Other polystyrene tubes were not significantly different from glass for storage of endotoxin or dilution water. Results of these studies indicate that while some tubes are well suited for use with the LAL test, others are not.