PT  - JOURNAL ARTICLE
AU  - Honorato Justicia
AU  - Modesto Ibanez
TI  - An Approach to the Determination of Endotoxin in Anesthetics and Antibiotics: Use of an Ultrafiltration System and Enzymatic LAL Reaction
DP  - 1993 Sep 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 205--210
VI  - 47
IP  - 5
4099  - http://journal.pda.org/content/47/5/205.short
4100  - http://journal.pda.org/content/47/5/205.full
SO  - PDA J Pharm Sci Technol1993 Sep 01; 47
AB  - An ultrafiltration system is used to obtain an endotoxin-free buffer for the LAL test. The procedure is combined with a kinetic LAL reaction of high sensitivity. This approach allows for the easy determination of endotoxin levels in parenterals with LAL-interfering substances, reducing the maximum valid dilution necessary for use in product development.