RT Journal Article
SR Electronic
T1 Gamma Processing Technology: An Alternative Technology for Terminal Sterilization of Parenterals
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 83
OP 89
VO 49
IS 2
A1 Reid, Brian D.
YR 1995
UL http://journal.pda.org/content/49/2/83.abstract
AB This paper will outline the advantages of utilizing gamma radiation as a means for terminally sterilizing parenterals and other pharmaceutical products. The factors which must be evaluated in order to qualify a product for radiation sterilization will be detailed. It will also compare the characteristics of this method with other technologies currently available. The highest SAL can be achieved by combining a knowledge of the microbial quality of the raw materials, and the manufacturing environment with a formulation designed to promote the most radiation stable form of the product.