@article {Duner119, author = {Kristina I. Duner}, title = {The Importance of the Quality of Water in Limulus Amebocyte Lysate Tests}, volume = {49}, number = {3}, pages = {119--121}, year = {1995}, publisher = {Parenteral Drug Association (PDA)}, abstract = {Commercial pharmaceutical waters were evaluated regarding their interference in the chromogenic Limulus Amebocyte Lysate (LAL) test. Two of the four tested waters strongly inhibited the U.S. Reference Standard Endotoxin, while a Control Standard Endotoxin was less affected. The inhibitory effect could be mimiced by adding trace amounts of certain metal ions to a non-interfering water. In conclusion, the water used in the LAL test must be chosen with great care.}, issn = {0006-3363}, URL = {https://journal.pda.org/content/49/3/119}, eprint = {https://journal.pda.org/content/49/3/119.full.pdf}, journal = {PDA Journal of Pharmaceutical Science and Technology} }