%0 Journal Article %A John D. Ludwig %A Craig W. Davis %T Automated Method for Determining Instron Residual Seal Force of Glass Vial/Rubber Closure Systems Part II. 13 mm vials %D 1995 %J PDA Journal of Pharmaceutical Science and Technology %P 253-256 %V 49 %N 5 %X Instron Residual Seal Force (IRSF) of 13 mm glass vial/rubber closure systems was determined using an Instron 4501 Materials Testing System and computerized data analysis. A series of three cap anvils varying in shape and dimensions were machined to optimize cap anvil performance. Cap anvils with spherical top surfaces and narrow internal dimensions produced uniform stress-deformation curves from which precise IRSF values were derived. %U https://journal.pda.org/content/pdajpst/49/5/253.full.pdf