PT - JOURNAL ARTICLE AU - De Jesus Andreoli Pinto, Terezinha AU - De Freitas Ribeiro, Alberto TI - The Influence of the Intravenous Catheter Composition on its Hemocompatibility DP - 1999 Jan 01 TA - PDA Journal of Pharmaceutical Science and Technology PG - 27--30 VI - 53 IP - 1 4099 - http://journal.pda.org/content/53/1/27.short 4100 - http://journal.pda.org/content/53/1/27.full SO - PDA J Pharm Sci Technol1999 Jan 01; 53 AB - Varied kinds of raw materials have been used for intravenous catheter manufacturing, raising important questions related to their hemocompatibility. In order to evaluate the influence of these materials on the hemocompatibility, different catheters—made of polyurethane (PU) (Vianont® or Tecoflext®), polytetrafluorethylene (PTFE) or polyvinyl chloride (PVC)—employed in 129 hospitalized patients, were analysed in this study. The used methodology involved careful catheter removal from patients, followed by chemical fixation and scanning electron microscopic evaluation of the adhered biological material. The results indicate that, on a decreasing scale of performance, PTFE catheters show better hemocompatibility than PU and PVC ones.