%0 Journal Article %A Ping Li %A Hemali Patel %A S. Esmail Tabibi %A Rao Vishnuvajjala %A Samuel H. Yalkowsky %T Evaluation of Intravenous Flavopiridol Formulations %D 1999 %J PDA Journal of Pharmaceutical Science and Technology %P 137-140 %V 53 %N 3 %X Flavopiridol is currently under consideration as a parenteral treatment of breast tumors. The solubility of this poorly water-soluble compound can be increased by a number of methods. However, because of its low water solubility, precipitation of the solubilized drug upon injection can be a problem. The potential of several flavopiridol formulations to precipitate is evaluated using a static serial dilution technique. It is shown that formulations containing up to 10 mg/mL of flavopiridol which produce negligible precipitation on dilution can be developed. %U https://journal.pda.org/content/pdajpst/53/3/137.full.pdf