PT  - JOURNAL ARTICLE
AU  - Stephens, Dennis
AU  - Bares, Dale
AU  - Robinson, Dan
AU  - Pec, Edward
TI  - Determination of Amylose/Particulate Relationship in Hydroxyethylstarch
DP  - 1999 Jul 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 181--185
VI  - 53
IP  - 4
4099  - http://journal.pda.org/content/53/4/181.short
4100  - http://journal.pda.org/content/53/4/181.full
SO  - PDA J Pharm Sci Technol1999 Jul 01; 53
AB  - Visual particulate was observed to form in parenteral hydroxyethylstarch over 24 months during stability studies. The particulate was identified as being amylose using FT-IR microscopy. Amylose values were measured in the bulk drug using the starch-iodine reaction. The amylose numbers measured in the bulk drug were found to correlate well with the measured particulate values in the parenteral formulation.