PT  - JOURNAL ARTICLE
AU  - Alexander Wekhof
TI  - Disinfection with Flash Lamps
DP  - 2000 May 01
TA  - PDA Journal of Pharmaceutical Science and Technology
PG  - 264--276
VI  - 54
IP  - 3
4099  - http://journal.pda.org/content/54/3/264.short
4100  - http://journal.pda.org/content/54/3/264.full
SO  - PDA J Pharm Sci Technol2000 May 01; 54
AB  - The analysis of published and new data on a pulsed disinfection is presented. It allows the conclusion that the pulsed disinfection mechanism includes both germicidal action of UVC light and a rupture of bacteria due to thermal stress, caused primarily by all UV components of the light pulse. The role of simultaneous cooling and heating of bacteria during a flash lamp pulse has been estimated and a direct detection of such a mechanism is proposed. It is suggested that an optimum pulsed light source for disinfection must have as much percentile content of a broad UV spectrum and a high peak power as is technically justified. Two new applications for pharmaceutics and medicine are suggested.