@article {Walther124, author = {Marten Walther and Volker Rupertus and Christina Seemann and Jutta Brecht and Robert Hormes and Robert W. Swift}, title = {Pharmaceutical Vials with Extremely High Chemical Inertness}, volume = {56}, number = {3}, pages = {124--129}, year = {2002}, publisher = {Parenteral Drug Association (PDA)}, abstract = {Traditional type I glass containers are becoming more unsuitable for packaging modern diagnostics and drugs. When using certain drugs (high-pH formulations, complexing agents, drugs with low dosage, sensitivity to pH-shift or ion release), product degradation can occur, reducing the drug{\textquoteright}s performance, potency, and shelf-life. To prevent chemical interaction between the container and the content, a coating technology applying a silicon dioxide layer to the internal container surface can bring the solution.}, issn = {0006-3363}, URL = {https://journal.pda.org/content/56/3/124}, eprint = {https://journal.pda.org/content/56/3/124.full.pdf}, journal = {PDA Journal of Pharmaceutical Science and Technology} }