RT Journal Article SR Electronic T1 Solid Dispersion Adsorbates for Enhancement of Dissolution Rates of Drugs JF PDA Journal of Pharmaceutical Science and Technology JO PDA J Pharm Sci Technol FD Parenteral Drug Association (PDA) SP 97 OP 101 VO 61 IS 2 A1 Deepti A1 Dureja, Harish A1 Madan, A.K. YR 2007 UL http://journal.pda.org/content/61/2/97.abstract AB Amalgamation of solid dispersion and melt adsorption technologies was utilized for enhancing the dissolution rate of poorly soluble drugs. Glibenclamide was employed as a model drug. PEG6000 and Gelucire44/14 were used as hydrophilic carriers for the preparation of solid dispersions, and lactose was utilized as an adsorbent for the preparation of solid dispersion adsorbates. A high dissolution rate of solid dispersion adsorbates was observed when compared to solid dispersions alone and one of the marketed products.