RT Journal Article SR Electronic T1 Characterization Methods for the Physical Stability of Biopharmaceuticals JF PDA Journal of Pharmaceutical Science and Technology JO PDA J Pharm Sci Technol FD Parenteral Drug Association (PDA) SP 429 OP 445 VO 57 IS 6 A1 Lida T. Nguyen A1 John M. Wiencek A1 Lee E. Kirsch YR 2003 UL http://journal.pda.org/content/57/6/429.abstract AB The characterization of protein aggregation and gelation using various methods, including scanning and transmission electron microscopy, small angle X-ray scattering, static light scattering, dynamic light scattering, infrared spectroscopy, Raman spectroscopy, rheology, and size exclusion chromatography (coupled with on-line laser light scattering, refractive index, and ultraviolet absorbance detection), are described in terms of theory and applications.