RT Journal Article
SR Electronic
T1 Comparative Study of the Swabbing Properties of Seven Commercially Available Swab Materials for Cleaning Verification
JF PDA Journal of Pharmaceutical Science and Technology
JO PDA J Pharm Sci Technol
FD Parenteral Drug Association (PDA)
SP 184
OP 193
VO 63
IS 2
A1 Damion K. Corrigan
A1 Sergey Piletsky
A1 Sean Mccrossen
YR 2009
UL http://journal.pda.org/content/63/2/184.abstract
AB This article compares the technical performances of several different commercially available swabbing materials for the purpose of cleaning verification. A steel surface was soiled with solutions of acetaminophen, nicotinic acid, diclofenac, and benzamidine and wiped with each swabbing material. The compounds were extracted with water or ethanol (depending on polarity of analyte) and their concentration in extract was quantified spectrophotometrically. The study also investigated swab debris on the wiped surface. The swab performances were compared and the best swab material was identified.